I take three bp meds. Used to take four including take hydrochlorothiazide. You can take it but the problem is it will lower your blood pressure which is the point. Until you get acclimated to a healthy bp you may feel dizzy, tired, or disconnected with your thoughts. The other issue is you may accidentally hand your choking buddy a pee bottle you made discretely when your medicine caused a urinary emergency. Best to clearly mark the container. Got my doc to take me off it.